With Canada's new cannabis regulations coming into effect later in 2018. WholeHemp is in the process of developing a line of full spectrum premium, artisanal organic hemp based CBD products. Please stay tuned and sign up for our newsletter to be the first to hear about upcoming news.
WHAT IS CBD?Cannabidiol (CBD) is one of the most prevalent chemical compounds in the cannabis/hemp plant. Unlike THC (tetrahydrocannabinol), CBD is non-intoxicating. CBD has been found to have numerous and amazingly beneficial therapeutic effects.
Pre-clinical trials conducted over the past four decades have found that the CBD shows promise as an:
|• Anti-inflammatory||• Anti-depressant||• Anti-oxidant|
|• Analgesic||• Neuroprotectant||• Anti-Tumoral Agent|
|• Anti-Anxiety Agent||• Anti-Psychotic|
While CBD is a powerful medicine on its own, it's important to note that the compound's effects are amplified when combined with other cannabinoids, something known as the 'entourage effect'. Cannabis is known to contain more than 100 cannabinoids, most in trace quantities. The entourage effect is the idea that combinations of cannabinoids work together in synergy to produce certain therapeutic effects.
A ground breaking 2015 study has documented the superior therapeutic properties of whole plant CBD-rich cannabis extract as compared to single-molecule cannabidiol (CBD)*1. This study showed that administration of pure, single-molecule CBD resulted in a bell-shaped dose-response curve, meaning that when the amount of CBD exceeded a certain point its therapeutic impact declined dramatically. "Healing was only observed when CBD was given within a very limited dose range, whereas no beneficial effect was achieved at either lower or higher doses." Rather than showing a bell-shaped curve, where at therapeutic effect could only be achieved at a certain concentration of pure CBD, the whole plant CBD-rich extract caused a direct, dose-dependent inhibition of pain, and inflammation. More over, the researchers found that only a small amount of whole plant CBD was needed for significant pain relief compared to the much larger amount of pure CBD required to achieve the same analgesic effect.
*1 - Gallily, R, et al (2015) "Overcoming the Bell Shaped Dose Response of Cannabidiol by Using Cannabis Extract Enriched in Cannabidiol," Pharmacology & Pharma, 6, 75-85.